CBD could be useful in treating depression, as it appears to have a positive interaction with serotonin receptors in the brain. CBD does not directly boost serotonin levels, but it affects how your brain’s chemical receptors respond to the serotonin that’s already present. A 2014 study found CBD had anti-depressive and anti-anxiety effects and a 2018 review concluded that CBD can reduce depression, specifically related to stress. Read more